At Longevity Health Clinic in Charlottesville, we specialize in cutting-edge therapies that work with your body’s natural processes to restore balance, heal injury, and optimize performance. One of the most exciting categories in regenerative and functional medicine today is peptide therapy.
Peptides are short chains of amino acids—essentially "mini-proteins"—that act as signaling molecules in the body. They regulate everything from hormone production to immune function, metabolism, inflammation, and tissue repair.
Harnessing these natural molecules offers targeted support for a wide range of conditions and symptoms, often with fewer side effects than traditional pharmaceuticals.
Mechanism: Both stimulate the pituitary gland to release more growth hormone (GH) by mimicking growth hormone-releasing hormone (GHRH). Sermorelin is a shorter analog; tesamorelin is slightly longer and more potent.
Health Focus: Improves body composition, recovery, sleep quality, and cognitive sharpness. Tesamorelin is particularly effective for visceral fat reduction.
Recommended Dosing:
Special Notes: Works best when paired with good sleep hygiene and regular exercise.
Mechanism: A synthetic tetrapeptide that activates telomerase, the enzyme responsible for extending telomeres, thereby promoting cellular longevity and delaying aging.
Health Focus: Anti-aging, improved circadian rhythms, immune modulation, cancer risk reduction.
Recommended Dosing:
Special Notes: Often used as part of a longevity optimization plan alongside mitochondrial support.
Mechanism: A mitochondrial-derived peptide that acts as a metabolic regulator. It enhances insulin sensitivity, promotes fat oxidation, improves exercise capacity, and supports cellular resilience.
Health Focus: Fat loss, insulin sensitivity, exercise endurance, metabolic flexibility.
Recommended Dosing:
Special Notes: Especially beneficial in individuals with metabolic syndrome or insulin resistance.
Mechanism: Inhibits the enzyme NNMT, leading to improved NAD+ metabolism and fat breakdown. It enhances adipose tissue browning (conversion of white fat to more metabolically active brown fat).
Health Focus: Fat loss, muscle preservation, metabolic optimization.
Recommended Dosing:
Special Notes: Often paired with intermittent fasting or ketogenic nutrition plans for synergy.
Mechanism: "Body Protection Compound" 157 is a peptide naturally found in gastric juice that promotes angiogenesis (new blood vessel formation), accelerates tissue repair, modulates the inflammatory response, and supports gut barrier integrity. It interacts with nitric oxide pathways and various growth factors to promote healing.
Health Focus: Tendon and ligament healing, gut repair (leaky gut, gut dysbiosis, inflammatory bowel disease [IBD]), joint recovery, brain injury support.
Recommended Dosing:
Special Notes: BPC-157 can be delivered via subcutaneous injections for musculoskeletal healing or oral formulations for targeted gut support, depending on the clinical goals. It’s often stacked with TB-500 for comprehensive recovery programs.
Mechanism: Regulates actin (critical for cell movement and structure), enhances tissue regeneration, reduces inflammation, and improves flexibility and strength in connective tissue.
Health Focus: Muscle healing, tendon/ligament injuries, post-surgical recovery.
Recommended Dosing:
Special Notes: Often combined with BPC-157 for synergistic healing effects.
Mechanism: Boosts the body's innate immune response by enhancing T-cell function, modulating inflammation, and improving antiviral defenses.
Health Focus: Immune enhancement, chronic infections, autoimmune disease modulation, cancer adjunct therapy.
Recommended Dosing:
Special Notes: Useful for long COVID, chronic EBV, and even preventive immune maintenance.
Mechanism: Regulates the endocrine and immune functions by interacting with the thymus gland, critical for T-cell maturation and immune response fine-tuning.
Health Focus: Immune balance, anti-inflammatory effects, support during immune suppression or autoimmune activity.
Recommended Dosing:
Special Notes: Often stacked with Thymosin Alpha-1 for synergistic immune rebuilding.
Peptide therapy represents a transformational tool in the world of functional medicine, regenerative healing, and longevity optimization.
By tapping into natural biological pathways, peptides can reverse symptoms, accelerate recovery, enhance performance, and extend healthspan—with a precision rarely matched by traditional pharmaceuticals.